QUANTITATIVE SCANNING OF OSTEOGENIC-SARCOMA WITH NITROGEN-13-LABELED L-GLUTAMATE

  • 1 January 1979
    • journal article
    • research article
    • Vol. 20  (7) , 782-784
Abstract
N-13-L glutamate was used to image an osteogenic sarcoma in a 9 yr old patient. Serial quantitative measurements of the amount of N-13 taken up by the primary tumor showed a decrease of 40% after 10 wk of chemotherapy. Blood-clearance data obtained from normal subjects indicate that more than 90% of the N-13 activity had left the blood before scanning of the tumor was begun. The N-13 label apparently concentrated in the soft-tissue portion of this osteogenic sarcoma, whereas Tc-99m diphosphonate uptake was greatest in the regions where calcification was occurring.