Iron Starvation Triggers the Stringent Response and Induces Amino Acid Biosynthesis for Bacillibactin Production in Bacillus subtilis
- 15 December 2006
- journal article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 188 (24) , 8655-8657
- https://doi.org/10.1128/jb.01049-06
Abstract
Iron deprivation in bacteria causes the derepression of genes controlled by the ferric uptake regulator (Fur). The present microarray analysis of iron-starved Bacillus subtilis cells grown in minimal medium unveils additional physiological effects on a large number of genes linked to stringent-response regulation and to genes involved in amino acid biosynthesis associated with pathways essential for bacillibactin production.Keywords
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