HYPOTHYROIDISM PRECEDING HYPERTHYROID GRAVES-DISEASE IN 2 CHILDREN

  • 1 January 1983
    • journal article
    • research article
    • Vol. 102, 27-32
Abstract
Two children with acquired hypothyroidism developed hyperthyroid Graves'' disease which was difficult to control. The cause of hypothyroidism was autoimmune thyroiditis in one case, in the other, autoimmune thyroiditis was suspected but not confirmed. Both children had thyrotropin-binding inhibiting Ig (TBII) in their sera. The TBII index was very low, in one of them even during the hypothyroid phase. Apparently, TBII reflect not only thyroid-stimulating, but also other thyrotropin receptor antibodies.

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