SYNTHESIS OF ALL PLASMA PROTEIN FRACTIONS EXCEPT GAMMA GLOBULINS BY THE LIVER

Abstract
Lysine-ϵ-C14-labeled plasma proteins produced by the normal rat and the isolated perfused rat liver have been fractionated by preparative zone electrophoresis. The isolated perfused liver incorporates lysine-ϵ-C14 into the plasma albumin, alpha globulin, and beta globulin (including fibrinogen) fractions. No significant C14 incorporation into the trichloracetic acid-precipitable proteins of the gamma globulin fraction was observed.