CONGENITAL SERUM PROTHROMBIN CONVERSION ACCELERATOR (SPCA) DEFICIENCY
- 1 August 1958
- journal article
- research article
- Published by American College of Physicians in Annals of Internal Medicine
- Vol. 49 (2) , 459-466
- https://doi.org/10.7326/0003-4819-49-2-459
Abstract
Coagulation studies performed on a 65-year-old white female with bleeding episodes from various sites since early childhood revealed the defect to be due to congenital serum prothrombin conversion accelerator (SPCA) deficiency. SPCA arises from a plasma precursor and is a relatively stable serum factor which, along with prothrombin, is adsorbed by BaSO4 and elutable by citrate. This is in contrast to plasma AC-globulin which is labile and not readily adsorbed by BaSO4.Keywords
This publication has 8 references indexed in Scilit:
- Congenital Hypoproconvertinemia.Experimental Biology and Medicine, 1953
- CONGENITAL FAMILIAL DEFICIENCY OF THE STABLE PROTHROMBIN CONVERSION FACTOR - RESTUDY OF CASE ORIGINALLY REPORTED AS IDIOPATHIC HYPOPROTHROMBINEMIA1953
- Prothrombin Conversion Factors in Blood CoagulationAmerican Journal of Physiology-Legacy Content, 1951
- Physiology and Pathology of Blood CoagulationActa Haematologica, 1951
- Co-Thromboplastin, a Probable Factor in Coagulation of BloodAmerican Journal of Physiology-Legacy Content, 1950
- THREE-STAGE ANALYSIS OF BLOOD COAGULATIONThe Journal of general physiology, 1948
- PLASMA ACCELERATOR GLOBULIN: PARTIAL PURIFICATION, QUANTITATIVE DETERMINATION, AND PROPERTIESJournal of Biological Chemistry, 1948
- The Function of Ac-Globulin in Blood ClottingScience, 1947