Bovine monoclonal antibodies specific for bovine herpesvirus-1 glycoprotein gIII
- 1 April 1990
- journal article
- research article
- Published by American Veterinary Medical Association (AVMA) in American Journal of Veterinary Research
- Vol. 51 (4) , 543-545
- https://doi.org/10.2460/ajvr.1990.51.04.543
Abstract
SUMMARY Spleen cells from a calf immunized with bovine herpesvirus-1 (BHV-1) were fused with the nonsecreting murine cell line SP2/0. Several bovine-murine hybridomas secreting bovine immunoglobulins were stabilized. Of these, 9 hybridomas secreted bovine monoclonal antibodies that specifically bound to BHV-1 in a radioimmunoassay. Two of these monoclonal antibodies reacted specifically with BHV-1 in an indirect fluorescent antibody test and immunoprecipitated a BHV-1 glycoprotein with molecular mass of 97 kilodaltons.This publication has 10 references indexed in Scilit:
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