Electron microscopic studies of circular DNA in mouse embryo fibroblasts infected by Rauscher leukemia virus
- 1 February 1977
- journal article
- research article
- Published by American Society for Microbiology in Journal of Virology
- Vol. 21 (2) , 792-795
- https://doi.org/10.1128/jvi.21.2.792-795.1977
Abstract
Using EM, a closed circular form of DNA (4.3 .mu.m in contour length) [presumed to be a late intermediate in the formation of integrated proviral DNA] was detected in the nucleus of mouse embryo fibroblasts 2.5 h after infection by Rauscher murine leukemia virus. These circles were distinguishable from mitochondrial DNA by various criteria, including size, absence of secondary features and resistance of EcoRI [restriction] endonuclease.This publication has 12 references indexed in Scilit:
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