Identification of ribosomal RNA genes in metagenomic fragments

Open Access

3 April 2009

journal article
research article
Published by Oxford University Press (OUP) in Bioinformatics

Vol. 25 (10) , 1338-1340
https://doi.org/10.1093/bioinformatics/btp161

Abstract

Motivation: Identification of genes coding for ribosomal RNA (rRNA) is considered an important goal in the analysis of data from metagenomics projects. Here, we report the development of a software program designed for the identification of rRNA genes from metagenomic fragments based on hidden Markov models (HMMs). This program provides rRNA gene predictions with high sensitivity and specificity on artificially fragmented genomic DNAs. Availability: Supplementary files, scripts and sample data are available at http://tools.camera.calit2.net/camera/meta_rna. Contact:liwz@sdsc.edu Supplementary information: Supplementary Data are available at Bioinformatics online.

Keywords

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