The molecular electrostatic potential of the B-DNA helix. VL The regions of the base pairs in poly (dG.dC) and poly (dA.dT)
- 1 January 1979
- journal article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 6 (12) , 3821-3830
- https://doi.org/10.1093/nar/6.12.3821
Abstract
The evaluation of the electrostatic molecular potential at important nucleophilic sites of the purine and pyrimidine bases in poly (dG.dC) and poly (dA.dT) and of the evolution of the potential through the series free bases-nucleosides-nucleotides-single polynucleotide helices-double helices enables the interpretation of the evolution of the corresponding reactivity of the bases towards a series of electrophilic carcinogenic and mutagenic reactants.Keywords
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