Role of homeobox genes in the patterning, specification, and differentiation of ectodermal appendages in mammals
Open Access
- 5 May 2008
- journal article
- review article
- Published by Wiley in Journal of Cellular Physiology
- Vol. 216 (2) , 337-346
- https://doi.org/10.1002/jcp.21491
Abstract
Homeobox genes are an evolutionarily conserved class of transcription factors that are key regulators during developmental processes such as regional specification, patterning, and differentiation. In this review, we summarize the expression pattern, loss‐ and/or gain‐of‐function mouse models, and naturally occurring mouse and human mutations of known homeobox genes required for the development of ectodermal appendages. J. Cell. Physiol. 216: 337–346, 2008.Keywords
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