Air slugs entrapped cross‐flow filtration of bacterial suspensions
- 5 March 1993
- journal article
- research article
- Published by Wiley in Biotechnology & Bioengineering
- Vol. 41 (5) , 525-530
- https://doi.org/10.1002/bit.260410504
Abstract
A novel cross‐flow technique for membrane filtration of bacterial cell suspensions was established. This is an air slugs entrapped cross‐flow method in which air slugs were generated by introducing air into the cross‐flow stream. As air slugs moved along with cross‐flow, the disturbance of cell sublayer formation on membrane surface was enhanced. As a consequence, filtration flux was improved and stabilized. The effect of air slugs on improving filtration flux was more pronounced in filtering gram‐negative Escherichia coli cell than grampositive Brevibacterium flavum cell. Moreover, air slug was about 50% more effective on reducing filtration resistance using ultrafiltration (UF) membrane of 300,000 molecular weight cutoff (MWCO) than microfiltration (MF) membrane of 0.2 μm. ©1993 John Wiley & Sons, Inc.Keywords
This publication has 8 references indexed in Scilit:
- Cross-flow filtration as a method of separating fungal cells and purifying the polysaccharide producedBioprocess and Biosystems Engineering, 1991
- Cross‐flow membrane microfiltration of a bacteriol fermentation brothBiotechnology & Bioengineering, 1989
- Dynamic filtration of microbial suspensions using an axially rotating filterJournal of Membrane Science, 1988
- Cross-flow membrane filtration of yeast suspensionsJournal of Biotechnology, 1987
- The separation of aryl acylamidase by cross flow microfiltration and the significance of enzyme/cell debris interactionJournal of Membrane Science, 1984
- Improvement of production of l-aspartic acid using immobilized microbial cellsApplied Microbiology and Biotechnology, 1984
- Tangential flow filtration ? A new method for the separation of bacterial enzymes from cell debrisBiotechnology Letters, 1983
- A filter fermenter-apparatus and control equipmentBiotechnology & Bioengineering, 1982