Potency Stability of Recombinant (Serine-17) Human Interferon-β
- 1 April 1987
- journal article
- research article
- Published by Mary Ann Liebert Inc in Journal of Interferon Research
- Vol. 7 (2) , 203-211
- https://doi.org/10.1089/jir.1987.7.203
Abstract
The antiviral activity of Escherichia coli-derived (Serine-17) human interferon-β, formulated with human serum albumin, is stable for 2 years when lyophilized and stored under refrigeration. This product shows an Arrhenius line fit for the stability of its activity when tested at multiple isothermal temperatures (25-80°C). In both isothermal and nonisothermal elevated temperature studies, increasing the level of human serum albumin in the formulation results in increased thermal stability.This publication has 6 references indexed in Scilit:
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