Recommendations for Post-Prostatectomy Radiation Therapy in the United States Before and After the Presentation of Randomized Trials
- 31 January 2011
- journal article
- Published by Wolters Kluwer Health in Journal of Urology
- Vol. 185 (1) , 116-120
- https://doi.org/10.1016/j.juro.2010.08.086
Abstract
Conclusions While men with involved margins and more aggressive pathological disease features were more likely to receive post-prostatectomy radiation therapy, recommendations for post-prostatectomy radiation did not increase after the initial reports from the randomized trials, perhaps because these studies initially reported improved biochemical disease-free survival but not overall survival. Whether the recent report of a survival benefit from adjuvant radiation therapy in the SWOG trial will impact patterns of care requires further followup.Keywords
This publication has 25 references indexed in Scilit:
- Phase III Postoperative Adjuvant Radiotherapy After Radical Prostatectomy Compared With Radical Prostatectomy Alone in pT3 Prostate Cancer With Postoperative Undetectable Prostate-Specific Antigen: ARO 96-02/AUO AP 09/95Journal of Clinical Oncology, 2009
- Adjuvant Radiotherapy for Pathological T3N0M0 Prostate Cancer Significantly Reduces Risk of Metastases and Improves Survival: Long-Term Followup of a Randomized Clinical TrialPublished by Wolters Kluwer Health ,2009
- Adjuvant Radiotherapy for Pathologically Advanced Prostate CancerJAMA, 2006
- Postoperative radiotherapy after radical prostatectomy: a randomised controlled trial (EORTC trial 22911)The Lancet, 2005
- Radical prostatectomy: pathology findings in 1001 cases compared with other major series and over timeBJU International, 2004
- THE IMPACT OF SURGICAL APPROACH (NERVE BUNDLE PRESERVATION VERSUS WIDE LOCAL EXCISION) ON SURGICAL MARGINS AND BIOCHEMICAL RECURRENCE FOLLOWING RADICAL PROSTATECTOMYJournal of Urology, 2004
- THE CONTEMPORARY MANAGEMENT OF PROSTATE CANCER IN THE UNITED STATES: LESSONS FROM THE CANCER OF THE PROSTATE STRATEGIC UROLOGIC RESEARCH ENDEAVOR (CAPSURE), A NATIONAL DISEASE REGISTRYJournal of Urology, 2004
- Comparison of surgery alone with surgery and adjuvant radiotherapy for pT3N0 prostate cancerBJU International, 2002
- BENEFIT OF ADJUVANT RADIATION THERAPY FOR LOCALIZED PROSTATE CANCER WITH A POSITIVE SURGICAL MARGINJournal of Urology, 2000
- Adjuvant radiotherapy for pathologic stage adenocarcinoma of the prostate: Ten-year updateInternational Journal of Radiation Oncology*Biology*Physics, 1995