Sickle Cell Crisis Associated With Drugs

Abstract
Drug overdose precipitated sickle cell crisis leading to death in four cases. Toxicologic studies in life and postmortem examinations showed the deaths to be caused by a combination of the ingested drugs and associated sickle cell crisis. Both the homozygous and heterozygous states in sickle cell disease are susceptible to sickle cell crisis induced by drug overdose.

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