B- and T-cell markers on human lymphoblasts after stimulation with mitogen or antigens.
- 1 October 1975
- journal article
- Vol. 22 (1) , 121-5
Abstract
Receptors for sheep erythrocytes and for the third component of complement were demonstrated on human lymphoblasts after stimulation with various antigens and mitogens. With these markers B- and T-cell stimulation could be differentiated. Phytohaemagglutinin (PHA) and purified protein derivative (PPD) proved to activate predominantly T cells, whereas foetal calf serum (FCS) was shown to be a B-cell stimulator. Candida albicans and allogeneic cells, on the other hand, stimulated both B and T cells.This publication has 17 references indexed in Scilit:
- Lymphocyte membrane receptors in cultures treated with mitogensCellular Immunology, 1974
- Lymphocyte activation. V. Quantitation of the proliferative responses to mitogens using defined T and B cell populations.1973
- Evidence for Transformation of Human B Lymphocytes by PHANature New Biology, 1973
- ISOLATION OF NORMAL T CELLS IN CHRONIC LYMPHATIC LEUKÆMIAThe Lancet, 1973
- SURFACE MARKERS ON HUMAN T AND B LYMPHOCYTESThe Journal of Experimental Medicine, 1972
- Receptors for complement and immunoglobulin on human leukemic cells and human lymphoblastoid cell linesJournal of Clinical Investigation, 1972
- Immunoglobulin light chain determinants on unstimulated and stimulated human blood lymphocytes, assayed by indirect immunofluorescence.1971
- Binding of Sheep Red Blood Cells to a Large Population of Human LymphocytesNature, 1971
- A POPULATION OF LYMPHOCYTES BEARING A MEMBRANE RECEPTOR FOR ANTIGEN-ANTIBODY-COMPLEMENT COMPLEXESThe Journal of Experimental Medicine, 1970
- THE CELLULAR BASIS OF IMMUNOLOGICAL RESPONSES: A Synthesis of Some Current ViewsThe Lancet, 1969