Fragile site in chromosome 12 in a patient with two miscarriages
- 1 November 1988
- journal article
- research article
- Published by Wiley in American Journal of Medical Genetics
- Vol. 31 (3) , 521-525
- https://doi.org/10.1002/ajmg.1320310306
Abstract
A heritable fragile site at 12q 13 is described in lymphocytes from a woman with a history of multiple miscarriage. The fragile site was not typically folate‐sensitive, being expressed in standard medium. The presence of this fragile site may have led to meiotic chromosome breakage and consequent infertility.Keywords
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