Abstract
This review of our work on resistance in Myzus persicae over the past 20 years is divided into three sections. After a brief introduction, the biochemistry of the resistance mechanism is discussed, followed by a description of how the understanding of this has been used to develop sensitive and reliable methods for monitoring resistance in field populations. Finally, recent work on the molecular genetic basis of the resistance mechanism is described, and its practical implications for understanding the build‐up of resistance in populations are discussed.

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