Occurrence and Fate of Fumonisins in Beef
- 1 January 1996
- book chapter
- Published by Springer Nature
- Vol. 392, 39-55
- https://doi.org/10.1007/978-1-4899-1379-1_4
Abstract
For 30 days, two groups of three steers each were fed a diet of herd-mix and alfalfa hay (control) or the diet with part of the herd-mix replaced by corn grits contaminated with 400μg/g FB1 and 130 μg/g FB2. Premortem examination involved liver functionality tests; serum analyses for AST, GGT, LDH, cholesterol, and total bilirubin; urinalysis; and analyses of the blood, urine, and feces for the presence of fumonisins or their metabolites. Postmortem examination involved necropsy, histopathology, and analysis of tissue for fumonisins. Results of the liver functionality test indicated some hepatobiliary compromise in the test animals. Unmetabolized FB1 and FB2 were detected in the feces (≥80%), whereas trace amounts were detected in the urine. Postmortem analysis of the tissues showed 2070 ng/g FB1 in the liver (SD: 1870), 97.3 ng/g FB1 in the muscle (SD: 41), and 23.4 ng/g FB1 in the kidney (SD: 8.7).Keywords
This publication has 16 references indexed in Scilit:
- Fumonisin B2 in Cultured Fusarium Proliferatum, M-6104, Causes Equine LeukoencephalomalaciaJournal of Veterinary Diagnostic Investigation, 1994
- Determination of the mycotoxin fumonisin B1 and identification of its partially hydrolysed metabolites in the faeces of non-human primatesFood and Chemical Toxicology, 1994
- Experimental Equine Leukoencephalomalacia, Toxic Hepatosis, and Encephalopathy Caused by Corn Naturally Contaminated with FumonisinsJournal of Veterinary Diagnostic Investigation, 1993
- Toxicity and carcinogenicity of the Fusanum monilzforine metabolite, fumonisin B1, in ratsCarcinogenesis: Integrative Cancer Research, 1991
- Pulmonary Edema and Hydrothorax in Swine Produced by Fumonisin B1, a Toxic Metabolite of Fusarium MoniliformeJournal of Veterinary Diagnostic Investigation, 1990
- Hepatotoxicity and renal toxicity in rats of corn samples associated with field cases of equine leukoencephalomalaciaFood and Chemical Toxicology, 1989
- Thermospray high performance liquid chromatographic/mass spectrometric analysis of some fusarium mycotoxinsJournal of High Resolution Chromatography, 1985
- Primary liver cancer and oesophageal basal cell hyperplasia in rats caused by fusarium moniliformeInternational Journal of Cancer, 1984
- Feed refusal in cattle associated with Fusarium moniliforme in cornPublished by Wiley ,1982
- Mycoflora of Corn Produced in Human Esophageal Cancer Areas in Transkei, Southern AfricaPhytopathology®, 1981