Association between IL-4 genotype and IL-4 production in the Japanese population
- 1 April 2002
- journal article
- research article
- Published by Springer Nature in Genes & Immunity
- Vol. 3 (2) , 107-109
- https://doi.org/10.1038/sj.gene.6363830
Abstract
We have identified that there are only two IL-4 gene haplotypes (I and II) in the Japanese population. There are significant differences among three genotypes (I/I, I/II and II/II) in the IL-4 producing proportion of peripheral Th cells using intracellular cytokine detection assay. These results make it likely that IL-4 genotype could influence the type of immune response.Keywords
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