Relative Increase of T Cells Expressing the Gamma/Delta Rather Than the Alpha/Beta Receptor in Ataxia-Telangiectasia
Open Access
- 11 January 1990
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 322 (2) , 73-76
- https://doi.org/10.1056/nejm199001113220201
Abstract
In ataxia—telangiectasia, B-cell and T-cell deficiencies are thought to be due to a defect of rearrangements of immunoglobulin and T-cell receptor genes. T cells recognize antigens through two types of CD3-associated receptors: α/β chains on mature cells and γ/δ chains mostly on immature cells.This publication has 22 references indexed in Scilit:
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