Determination of the colonization resistance of the digestive tract of individual mice
- 1 February 1974
- journal article
- research article
- Published by Cambridge University Press (CUP) in Epidemiology and Infection
- Vol. 72 (3) , 379-387
- https://doi.org/10.1017/s0022172400023615
Abstract
SUMMARY: It has been shown that it is possible to investigate the colonization resistance in individual mice by determining the concentration of a certain contaminant (S.R.-E. coli) in the faeces during the first 4 days after contamination. Experimental contamination is contra-indicated in many cases such as in individuals with decreased resistance to infection. Particularly in this group, the value of the colonization resistance should be determined. It appeared to be possible to determine the colonization resistance in such individuals by quantitative biotyping of the Enterobacteriaceae species in the faeces on several consecutive days.Keywords
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