THE INFLUENCE OF VITAMIN A UPON UREA CLEARANCE IN THE HUMAN SUBJECT 1

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Abstract
Vit. A in the form of a concentrate of halibut liver oil or the entire oi]l was administered in daily doses varying from 50,000 to 75,000 I. U. to 10 [male] and 3 [female] adults. In 2 subjects there was no appreciable change in urea clear-ance, in 4 subjects the clearance increased 11-15%, and in 7 subjects the clearance elevation ranged from 24-91%. The subjects in this latter group were the type who easily gain in body wt. The increase in clearance in 2 subjects was not accompanied by significant changes in blood pressure or O2 consumption.

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