Hormones and the Metabolic Response to Injury

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Abstract
It is now nearly 50 years since the metabolic response to injury was described by Sir David Cuthbertson,1 who happily still studies this interesting phenomenon. During the intervening half-century, including a World War and a progressive increase in civilian accident injuries, we continue to seek rational explanations and treatments for the loss of body protein that accompanies various traumatic incidents. This issue of the Journal contains an article by Allison and his colleagues, who find that patients with a severe catabolic response after trauma show a considerable reduction in urea production when large doses of insulin are given along with . . .