The determination of iron in plasma or serum

Abstract
Using Fe59, it was shown that iron is effectively separated from beta1 -globulin in plasma by treatment with dilute HC1 and trichloracetic acid (TCA). A simple and rapid method for the determination of Fe in plasma is described. Two ml of 2[image] - HCl is added to 4 ml of plasma and after stirring, 2 ml of 20% TCA added, the mixture stirred for 45 seconds and centrifuged. The supernatant is added to 0.5 ml of 0.4% 2:2'' dipyridyl plus 2.5 ml saturated sodium acetate plus 2 drops of thioglycollic acid and the color intensity measured in a colorimeter with 520-m[mu] filter.

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