Lethal Effect of Chlorpromazine on the Chick Embryo.
- 1 November 1963
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 114 (2) , 398-400
- https://doi.org/10.3181/00379727-114-28689
Abstract
Summary Chlorpromazine, injected into the yolk sac of fertile hens' eggs, is lethal to a high percentage of embryos. At dosage levels of 0.9 and 1.8 mg the compound is destructive if it is administered within the first 48 hours of incubation; it shows little effect at 72 hours, and none at 96 hours.Keywords
This publication has 15 references indexed in Scilit:
- Interference of Chlorpromazine with the Metabolism of Aromatic Amino-acids in Rat BrainNature, 1962
- Chlorpromazine Affects Permeability of Resting Cells of Tetrahymena pyriformisScience, 1962
- ACTION OF ANTIHISTAMINE AND OTHER DRUGS ON ION AND WATER MOVEMENTS IN CELLS AND MITOCHONDRIA1962
- Influence of chlorpromazine on decarboxylases of aromatic amino acidsBiochemical Pharmacology, 1961
- Action de quelques phénothiazines et iminodibenzyles sur la division cellulaire et sur certains processus de croissanceChemotherapy, 1961
- INFLUENCE OF CHLORPROMAZINE AND CHLORPROTHIXENE ON CEREBRAL METABOLISM OF 5-HYDROXYTRYPTAMINE, NOREPINEPHRINE AND DOPAMINE1961
- The action of chlorpromazine on yeast hexokinaseBiochemical Pharmacology, 1960
- THE IN VITRO AND IN VIVO EFFECTS OF CHLORPROMAZINE ON BRAIN LIPID SYNTHESISJournal of Neurochemistry, 1960
- Mechanism of inhibition of D-amino acid oxidase IV. Inhibitory action of chlorpromazineBiochimica et Biophysica Acta, 1960
- PROPRIETES PHARMACODYNAMIQUES DU CHLORHYDRATE DE CHLORO-3 (DIMETHYLAMINO-3 PROPYL)-10 PHENOTHIAZINE (4 560 R P) - ETUDE EXPERIMENTALE DUN NOUVEAU CORPS UTILISE DANS LANESTHESIE POTENTIALISEE ET DANS LHIBERNATION ARTIFICIELLE1952