Distinct Mechanisms for Regulating the Tumor Suppressor and Antiapoptotic Functions of Rb
Open Access
- 1 May 2003
- journal article
- Published by Elsevier
- Vol. 278 (21) , 19358-19366
- https://doi.org/10.1074/jbc.m301761200
Abstract
No abstract availableKeywords
This publication has 41 references indexed in Scilit:
- Retinoblastoma Tumor Suppressor Protein Signals through Inhibition of Cyclin-Dependent Kinase 2 Activity To Disrupt PCNA Function in S PhaseMolecular and Cellular Biology, 2001
- Collective Inhibition of pRB Family Proteins by Phosphorylation in Cells with p16INK4a Loss or Cyclin E OverexpressionJournal of Biological Chemistry, 2001
- Exit from G1 and S Phase of the Cell Cycle Is Regulated by Repressor Complexes Containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNFCell, 2000
- p16INK4a, but not constitutively active pRb, can impose a sustained G1 arrest: molecular mechanisms and implications for oncogenesisOncogene, 1999
- pRB phosphorylation mutants reveal role of pRB in regulating S phase completion by a mechanism independent of E2FOncogene, 1998
- Apoptosis is associated with cleavage of a 5 kDa fragment from RB which mimics dephosphorylation and modulates E2F bindingOncogene, 1997
- Cancer Cell CyclesScience, 1996
- Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesisNature, 1992
- Effects of an Rb mutation in the mouseNature, 1992
- The retinoblastoma susceptibility gene product undergoes cell cycle-dependent dephosphorylation and binding to and release from SV40 large TCell, 1990