AMNIOTIC-FLUID PHOSPHATIDYLGLYCEROL AND PHOSPHATIDYLINOSITOL SEPARATED BY STEPWISE-DEVELOPMENT THIN-LAYER CHROMATOGRAPHY

  • 1 January 1980
    • journal article
    • research article
    • Vol. 26  (2) , 277-281
Abstract
A stepwise-development TLC technique is described for separating phosphatidylglycerol and phosphatidylinositol in samples of amniotic fluid. Plates are prepared from silica gel G slurried in a 50 g/l ammonium sulfate solution. Phospholipid phosphorus determination is not needed. Phosphatidylglycerol and phosphatidylinositol, measured densitometrically, are expressed as ratios to the sphingomyelin present. These ratios are correlated with the lecithin/sphingomyelin ratio and age of gestation in normal and abnormal [human] pregnancies.