The Human Hemoglobins in Health and Disease

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Abstract
Fetal Hemoglobin in Normal and Pathologic ConditionsAlthough fetal hemoglobin has been recognized since 186619 its occurrence in normal and pathologic states has been extensively investigated only during the past few years.20,30,73,114, 116 117 118 119 120 121 122 123 124 125 Hgb F appears at the time red cells are first developed in the fetus and is probably the only type of blood pigment present until Hgb A production starts at about the fifth or sixth intrauterine month. At birth 55 to 85 per cent of the hemoglobin is in the embryonic form, after which there is a rapid decrease to normal adult levels120 (Fig. 6). Contrary to numerous . . .