The Weight and Mortality Response of Male and Female Mice in the Lethal X-Ray Dose Range

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Abstract
The effects of total body X-irradiation on the body weight changes of approximately 12,000 male and female mice were analyzed for a series of publications. The data obtained during a single year (1949), showing the uniformity of the biological, environmental, and radiological factors employed in these studies, and the general characteristics of the weight and mortality response in the lethal radiation dose range are described in this 1st report. Male mice showed proportionately greater changes in weight than females and the mortality of the males was consistently greater than that of females exposed to the same respective doses of radiation.