Dissecting the complexity of the nervous system by enhancer detection
- 1 May 1990
- Vol. 12 (5) , 199-204
- https://doi.org/10.1002/bies.950120502
Abstract
Enhancer detectors are DNA constructs which, when introduced into a eukaryotic genome, respond to nearby genomic transcriptional regulatory elements by means of a reporter gene, revealing the expression pattern of genes in their vicinity. Recent experiments in Drosophila suggest that enhancer detection is a powerful method to identify genes that are expressed in the nervous system. Since enhancer detectors allow a rapid molecular and genetic characterization of genes in their vicinity, the method will greatly facilitate the study of neural development and behavior.Keywords
This publication has 26 references indexed in Scilit:
- P-element-mediated enhancer detection: an efficient method for isolating and characterizing developmentally regulated genes in Drosophila.Genes & Development, 1989
- P-element-mediated enhancer detection: a versatile method to study development in Drosophila.Genes & Development, 1989
- Searching for pattern and mutation in the Drosophila genome with a P-lacZ vector.Genes & Development, 1989
- Genesis of the Drosophila peripheral nervous systemTrends in Genetics, 1989
- Drosophila adhesion molecules and neural developmentTrends in Neurosciences, 1988
- Neurogenetic Dissection of Learning and Short-Term Memory in DrosophilaAnnual Review of Neuroscience, 1988
- Characterization and cloning of fasciclin III: A glycoprotein expressed on a subset of neurons and axon pathways in DrosophilaCell, 1987
- Are the structural changes in adultDrosophilamushroom bodies memory traces? Studies on biochemical learning mutantsJournal of Neurogenetics, 1987
- NEUROGENETICS OF MEMBRANE EXCITABILITY IN DROSOPHILAAnnual Review of Genetics, 1986
- Genetic Transformation of Drosophila with Transposable Element VectorsScience, 1982