Analysis of histone in situ in developmentally inactivated chromatin.
- 1 August 1965
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 54 (2) , 476-480
- https://doi.org/10.1073/pnas.54.2.476
Abstract
Evidence is presented, from fast green staining, for a quantitative difference in histories between euchromatin and heterochromatin which is genetically inactive and fails to metabolize RNA. No cytochemically measurable difference in lysine/arginine ratios of the 2 histones was noted. Both hetero- and euchromatin undergo a spermatogenic histone transition similar to that of Drosophila and other organisms; unlike other organisms, nongametogenic tissues of the testes also undergo this transition. These findings are shown to conform to either or both of the 2 predominant theories of the involvement of histone with cell differentiation.This publication has 16 references indexed in Scilit:
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