Abstract
The effect of pH on fumarase activity in the absence of inorganic anions is descr. Sulfate (and selenate), arsenite, citrate, borate, phosphate and arsenate, in increasing order of effectiveness, activate salt-free fumarase [from pig heart] and alter the optimal pH. Chloride, bromide, thiocyanate and iodide, in increasing order of effectiveness, inhibit the action of fumarase, either in the presence or absence of activating anions. The extent of the inhibition is markedly dependent on the pH.

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