Urine Acidification with Methionine and Its Effect on Stone Formation in the Rat

Publisher Website
Google Scholar
Abstract
Male Harlan rats developed magnesium ammonium phosphate stones and female Holtzman calcium phosphate calculi after introduction of a metallic foreign body into the bladder. The addition of DL methionine to the Purina chow diet (1 gm%) prevented growth of magnesium but not of calcium stones. In the presence of Proteus infection the medication was ineffective.