Comparative Effect of Aureomycin and Chloromycetin on Psittacosis Infection in Chick Embryos.

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Abstract
Both aureomycin and chloromycetin prolong the life of chick embryos infected with the 6BC strain of psittacosis virus. There is a direct relation between the dose of antibiotic and the prolongation of life of the embryos, the infecting dose being kept constant. With equal doses of antibiotics, aureomycin prolonged the life of the embryos for an avg. of from 2 to more than 3 days longer than chloromycetin, depending on the dose used. On a wt. basis, aureomycin was more than 3 times as effective in protecting chick embryos against the dose of virus that was used in this study. On a molecular basis, the aureomycin was more than 5 times as effective as chloromycetin in this infection.