Eating ability in head and neck cancer patients after treatment with chemoradiation: A 12‐month follow‐up study accounting for dropout
- 23 June 2003
- journal article
- research article
- Published by Wiley in Head & Neck
- Vol. 25 (12) , 1034-1041
- https://doi.org/10.1002/hed.10317
Abstract
Background.: Head and neck cancer patients treated with chemoradiation have difficulty eating a normal diet. This study was designed to characterize eating ability over 12 months after chemoradiation treatment. Analyses take patient dropout into account.Methods: Two hundred fifty‐five patients with head and neck cancer treated with chemoradiation were followed for 12 months. Eating ability was analyzed using generalized linear model methods that accounted for non‐ignorable dropout.Results.: Eating ability was compromised immediately after treatment and improved over 12 months to near pretreatment levels. Ability to eat at most 50% of the diet orally did not return to baseline levels (p < .05). However, the percent of patients eating a normal diet did return to baseline levels. Accounting for dropout modified the results, but the pattern of significance was similar.Conclusions.: Treatment of head and neck cancer with chemoradiation has a significant effect on eating ability, which improves after 12 months after treatment. © 2003 Wiley Periodicals, Inc. Head Neck 25: 000–000, 2003Keywords
This publication has 18 references indexed in Scilit:
- Follow-up in patients with oral cancerJournal of Oral and Maxillofacial Surgery, 2002
- Swallowing rehabilitation after oro-pharyngeal resection for squamous cell carcinomaBritish Journal of Oral and Maxillofacial Surgery, 2000
- Relating speech and swallow function to dropout in a longitudinal study of head and neck cancerOtolaryngology -- Head and Neck Surgery, 1999
- Application of random-effects pattern-mixture models for missing data in longitudinal studies.Psychological Methods, 1997
- Quality of life outcomes after primary radiotherapy for squamous cell carcinoma of the base of tongueInternational Journal of Radiation Oncology*Biology*Physics, 1996
- Swallowing Disorders in Head and Neck Cancer Patients Treated With Radiotherapy and Adjuvant ChemotherapyThe Laryngoscope, 1996
- A return to “normal eating” after curative treatment for oral cancer. What are the long-term prospects?Oral Oncology, 1994
- Speech and swallowing function after oral and oropharyngeal resections: One‐year follow‐upHead & Neck, 1994
- Generalized Linear ModelsPublished by Springer Nature ,1989
- Longitudinal data analysis using generalized linear modelsBiometrika, 1986