A method for preparing smallpox vaccine on a large scale in cultured cells
- 1 June 1961
- journal article
- research article
- Published by Cambridge University Press (CUP) in Epidemiology and Infection
- Vol. 59 (2) , 171-180
- https://doi.org/10.1017/s0022172400038833
Abstract
A tissue culture system using chick embryo cells gave bacteria-free vaccinia virus suspensions of sufficient potency to use as a vaccine. Clinical trials with vaccines prepared by this method gave similar results to those with sheep lymph vaccine.Keywords
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