Asymmetric catalysis with bifunctional cinchona alkaloid-based urea and thiourea organocatalysts
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Open Access
- 21 February 2008
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Chemical Communications
- No. 22,p. 2499-2510
- https://doi.org/10.1039/b719249e
Abstract
Cinchona alkaloid derivatives modified to include a (thio)urea component have emerged in the last three years as readily accessible, robust and tunable bifunctional organocatalysts for a range of synthetically useful transformations. The origins of these catalysts and the major developments in their application in enantioselective synthesis are reviewed.Keywords
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