Short term metronidazole therapy contrasted with povidone-iodine spray in the prevention of wound infection after appendicectomy

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Abstract
Summary: In a prospective, randomized trial metronidazole was found to be significantly better than povidone-iodine in reducing the incidence of wound infection after appendicectomy (P < 0.005). The metronidazole was given as a 3-day course and was found to be as effective as the established 7-day course. Over 65 per cent of the wound infections presented after the patients had been discharged from hospital.