PATHOGENESIS OF CHRONIC DISEASE ASSOCIATED WITH PERSISTENT LYMPHOCYTIC CHORIOMENINGITIS VIRAL INFECTION
Open Access
- 1 March 1969
- journal article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 129 (3) , 483-505
- https://doi.org/10.1084/jem.129.3.483
Abstract
Mice infected shortly after birth with lymphocytic choriomeningitis (LCM) virus are not immunologically tolerant, although they carry the virus throughout life. These LCM carrier mice make anti-LCM antibody, which apparently complexes with viral antigen in the circulation and these complexes accumulate in the glomeruli.Keywords
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