Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex
Open Access
- 31 October 2003
- journal article
- research article
- Published by Elsevier in Chemistry & Biology
- Vol. 10 (11) , 1065-1076
- https://doi.org/10.1016/j.chembiol.2003.10.007
Abstract
No abstract availableKeywords
This publication has 39 references indexed in Scilit:
- How do the polyene macrolide antibiotics affect the cellular membrane properties?Published by Elsevier ,2003
- The candicidin gene cluster from Streptomyces griseus IMRU 3570 The GenBank accession numbers for the sequences reported in this paper are AJ300302 and AJ300303.Microbiology, 2002
- Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genesChemistry & Biology, 2001
- A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensisChemistry & Biology, 2000
- Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathwayChemistry & Biology, 2000
- The biosynthetic gene cluster for the macrolactone ring of the immunosuppressant FK506European Journal of Biochemistry, 1998
- The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.Proceedings of the National Academy of Sciences, 1995
- Deletion analysis of the avermectin biosynthetic genes of Streptomyces avermitilis by gene cluster displacementJournal of Bacteriology, 1993
- Modular Organization of Genes Required for Complex Polyketide BiosynthesisScience, 1991
- An unusually large multifunctional polypeptide in the erythromycin-producing polyketide synthase of Saccharopolyspora erythraeaNature, 1990