Tumor Angiogenesis and p53 Mutations

Abstract
IN CURRENT clinical practice, the treatment of head and neck squamous cell carcinoma (HNSCC) is based on the histological grade and TNM stage. However, these measures have limited predictive value for therapeutic results. Recognition of additional prognostic markers is clearly needed to subdivide the HNSCC patient population into those who respond well and poorly to different modes or combinations of therapy.