Serum Albumin ‐ A Non‐Saturable Carrier
- 1 February 1984
- journal article
- research article
- Published by Wiley in Acta Pharmacologica et Toxicologica
- Vol. 54 (2) , 129-133
- https://doi.org/10.1111/j.1600-0773.1984.tb01906.x
Abstract
The shape of binding isotherms for sixteen ligands to human serum albumin showed no signs of approaching saturation at high ligand concentrations. It is suggested that ligand binding to serum albumin is essentially different from saturable binding of substrates to enzymes, of oxygen to haemoglobin, etc. Binding to serum albumin appears to be non-saturable.Keywords
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