Effect of cysteine on respiration and catalyse synthesis by Saccharomyces cerevisiae

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Abstract
Freshly harvested cells of S. cerevisiae grown anaerobically exhibited a lag period before they were able to oxidize glucose under aerobic conditions. This lag period was avoided if the cells were first aerated in the presence of glucose. L-Cysteine produced a marked inhibition of both yeast respiration and catalase synthesis. Ferric ammonium citrate reversed this inhibition. Ethanol was ineffective. Of compounds related to cysteine, cystine and methionine were noninhibitory, whereas homocysteine and glutathione were slightly inhibitory.