Screening oocytes and preimplantation embryos for aneuploidy
- 1 June 1999
- journal article
- review article
- Published by Wolters Kluwer Health in Current Opinion in Obstetrics and Gynecology
- Vol. 11 (3) , 301-305
- https://doi.org/10.1097/00001703-199906000-00012
Abstract
Pregnancy and live birth rates following in-vitro fertilization decline rapidly with advancing maternal age partly because of an increase in age-related aneuploidies occurring in female meiosis. Screening oocytes or preimplantation embryos for common aneuploidies is now possible by polar body or cleavage stage biopsy and multicolour fluorescence in-situ hybridization.Keywords
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