CEREBRAL BLOOD FLOW AND OXYGEN CONSUMPTION IN HYPERTHYROIDISM BEFORE AND AFTER TREATMENT 1

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Abstract
Studies of cerebral blood flow, cerebral vascular resistance, and cerebral oxygen consumption, as well as mean arterial blood pressure, hemoglobin concn., blood gases, and blood pH, were made on 11 untreated hyperthyroid patients and then repeated on 7 following treatment. Cerebral oxygen consumption was normal and was not significantly correlated with BMR. A moderate elevation of cerebral blood flow was noted in untreated hyperthyroidism probably because of an associated anemia. Mean arterial blood pressure was normal, but cerebral vascular resistance was low for this age group. Except for the low oxygen contents associated with a moderate anemia, blood gases were found to be within normal limits. Treatment induced a decrease in BMR to normal level and an increase in cerebral respiratory quotient.