Biosynthesis of vitamin B12: identity of fragment extruded during ring contraction to the corrin macrocycle.
- 1 January 1981
- journal article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 78 (1) , 13-15
- https://doi.org/10.1073/pnas.78.1.13
Abstract
Incorporation experiments with labeled sirohydrochlorin and trimethylisobacteriochlorin demonstrate that ring contraction in vivo to the corrin macrocycle of vitamin B12 liberates acetic acid. The C-20 atom of the precursors becomes the acetate carboxyl carbon.Keywords
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