On the Biosynthesis of Lichen Substances. Part 1. The Depside Gyrophoric Acid.

Abstract
A method for the in vivo study of the biosynthesis of lichen metabolites has been developed. By the administration of diethyl malonate-1-C14, radioactive gyrophoric acid has been obtained with an incorporation of 2% of the added radioactivity. Results from the chemical degradation of this lichen metabolite clearly indicate that the biosynthesis follows the pattern of "acetate-polymalonate"-derived compounds known from other microorganisms.

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