Agitation of the solvent in tablet dissolution studies—a flow visualization technique
- 1 May 1972
- journal article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 24 (5) , 345-351
- https://doi.org/10.1111/j.2042-7158.1972.tb09005.x
Abstract
A flow visualization technique has been used to compare flow patterns in several kinds of dissolution apparatus in wide use. The technique readily reveals undesirable characteristics and provides a rational basis for judging empirically developed dissolution apparatus. Some undesirable mixing and flow characteristics were seen in all the methods examined. The U.S.P. apparatus appeared the most promising.Keywords
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