Effect of Corticotropin and Cortisone on Globule Leucocytes of Rat.

Abstract
Treatment by subcut. injns. of 1 mg. of corticotropin or 5 mg. of cortisone daily for 21 days caused a marked decline in the population of globule leukocytes in the tracheal mucosa of rats. Admn. of 6 mg. corticotropin or 10 mg. cortisone daily caused these cells to disappear almost completely. In this response the globule leukocyte resembles the lymphocyte.