Presence of H‐Y antigen in female patients with sex‐chromosome mosaics and absence of testicular tissue
- 2 June 1983
- journal article
- research article
- Published by Wiley in American Journal of Medical Genetics
- Vol. 15 (2) , 315-321
- https://doi.org/10.1002/ajmg.1320150215
Abstract
H‐Y antigen was tested in five women with sex chromosome mosaicism and gonadal streaks. Three patients had a 45,X/46,XY or 46,X,der(Y) and two a 45,X/46,X,der(X) chromosome constitution. All patients were H‐Y antigen positive. Lack of testis differentiation in these women may be explained by subthreshold expression of H‐Y antigen, different H‐Y antigen molecules, and/or different tissue distribution of the chromosome mosaicism.Keywords
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